Research & LAB

What’s cell mechanics?

Cell mechanics is a field of study that focuses on the mechanical properties and behavior of cells, which are the basic building blocks of life. This field combines principles from physics, engineering, and biology to understand how cells respond to mechanical forces, such as stretching, compression, or shear stress. Cell mechanics has a wide range of applications, including tissue engineering, regenerative medicine, and cancer research.

One of the key areas of research in cell mechanics is the study of cell deformation and shape change. Researchers use techniques such as atomic force microscopy, optical tweezers, and micropipette aspiration to apply controlled mechanical forces to cells and observe how they respond. By studying how cells deform and change shape, researchers can gain insights into the mechanical properties of cells and the underlying biological processes that govern their behavior.

Cell mechanics is also important in the development of tissue engineering and regenerative medicine strategies. Researchers use biomechanical principles to design scaffolds and other structures that can support the growth and function of cells, tissues, and organs. By understanding the mechanical properties of cells and the extracellular matrix, researchers can design scaffolds that mimic the natural mechanical environment of the body, promoting the growth and function of cells and tissues.

In addition to tissue engineering and regenerative medicine, cell mechanics has implications for cancer research. Researchers have found that cancer cells exhibit different mechanical properties than normal cells, such as increased stiffness and decreased deformability. By studying these differences, researchers can develop new diagnostic and therapeutic strategies for cancer, such as mechanical probes that can detect cancer cells in tissue samples or treatments that target the mechanical properties of cancer cells.

Overall, cell mechanics is a diverse and rapidly evolving field that has many practical applications in areas ranging from tissue engineering and regenerative medicine to cancer research and diagnostics. By studying the mechanical properties of cells, researchers can gain new insights into the underlying biological processes that govern cell behavior and develop new technologies and strategies for improving human health and wellbeing.

Magnetic Tweezer Cytometery

Atomic Force Microscopy